カトウ ケイコ   KATO KEIKO
  加藤 啓子
   所属   京都産業大学  生命科学部 先端生命科学科
   職種   教授
期間 1994/07
名称 BASAL MAGNOCELLULAR AND PONTINE CHOLINERGIC NEURONS COEXPRESS FGF RECEPTOR MESSENGER-RNA
区分 その他
開催場所 ELSEVIER SCI IRELAND LTD NEUROSCIENCE RESEARCH
発表者・共同発表者等 S YOSHIDA,LP LIN,ZL CHEN,Y MOMOTA,K KATO,T TANAKA,A WANAKA,S SHIOSAKA
発表・展示等 By in situ hybridization histochemistry, fibroblast growth factor receptor gene (flg)-expressing neurons were newly identified in the basal magnocellular nuclei (the vertical and horizontal limbs of the diagonal band, and Meynert's nucleus). The present study also confirmed flg localization in the laterodorsal tegmental nucleus and the pedunculopontine tegmental nucleus of the pens. Immuno- and in situ hybridization histochemistry on the same sections demonstrated that choline acetyltransferase and flg were colocalized in single neurons of the diagonal band, Meynert's nucleus and the pontine tegmental areas. The results suggest that a significant number of the basal magnocellular and a majority of the mesopontine cholinergic neurons are directly affected by fibroblast growth factors (FGF) via FGF receptor gene.
DOI 10.1016/0168-0102(94)90020-5