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カトウ ケイコ
KATO KEIKO
加藤 啓子 所属 京都産業大学 生命科学部 先端生命科学科 職種 教授 |
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| 期間 | 1995/07 |
| 名称 | EXPRESSION AND ACTIVITY-DEPENDENT CHANGES OF A NOVEL LIMBIC-SERINE PROTEASE GENE IN THE HIPPOCAMPUS |
| 区分 | その他 |
| 開催場所 | SOC NEUROSCIENCE JOURNAL OF NEUROSCIENCE |
| 発表者・共同発表者等 | ZL CHEN,S YOSHIDA,K KATO,Y MOMOTA,J SUZUKI,T TANAKA,J ITO,H NISHINO,S AIMOTO,H KIYAMA,S SHIOSAKA |
| 発表・展示等 | A novel murine cDNA which encodes a protein designated neuropsin was cloned, Northern and in situ hybridization analyses demonstrated that neuropsin mRNA is expressed specifically in the limbic system of mouse brain and is localized at highest concentration in pyramidal neurons of the hippocampal CA1-3 subfields. Direct hippocampal stimulation and kindling induced by amygdaloid stimulation caused a significant bilateral change in neuropsin mRNA level in the hippocampal pyramidal neurons, The activity-dependent changes and the specific localization indicate that neuropsin is involved in hippocampal plasticity. |