イタノ ナオキ   ITANO NAOKI
  板野 直樹
   所属   京都産業大学  生命科学部 先端生命科学科
   職種   教授
言語種別 英語
発行・発表の年月 1996/05
形態種別 研究論文
査読 査読あり
標題 Molecular cloning of human hyaluronan synthase
執筆形態 その他
掲載誌名 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
出版社・発行元 ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS
巻・号・頁 222(3),pp.816-820
著者・共著者 N Itano,K Kimata
概要 We report here the cDNA sequence of human hyaluronan synthase. The cDNA clone was isolated from a human fetal brain cDNA library by screening with a DNA probe generated from the coding sequence of murine hyaluronan synthase. It contains a 2107 bp cDNA insert which is composed of a 1629 bp open reading frame and a short segment of the 3'-untranslated region. Comparative analysis of the predicted coding region with the murine hyaluronan synthase sequence indicates 84.4% and 96.0% identity in nucleotide sequence and amino acid sequences, respectively. Northern analysis indicated that the gene was ubiquitously expressed in various human tissues. (C) 1996 Academic Press, Inc.
ISSN 0006-291X