ハマノ ツヨシ   HAMANO TSUYOSHI
  濱野 強
   所属   京都産業大学  現代社会学部 健康スポーツ社会学科
   職種   教授
言語種別 英語
発行・発表の年月 2019
形態種別 研究論文
査読 査読あり
標題 J-curve association between alcohol intake and varicose veins in Japan: The Shimane CoHRE Study.
執筆形態 その他
掲載誌名 The Journal of dermatology
掲載区分国外
巻・号・頁 46(10),pp.902-906
著者・共著者 Kunie Kohno,Hiroyuki Niihara,Tsuyoshi Hamano,Miwako Takeda,Yusei Nakagawa,Kuninori Shiwaku,Toru Nabika,Bengt Zöller,Xinjun Li,Kristina Sundquist,Jan Sundquist,Eishin Morita
概要 The effect of alcohol intake on varicose veins (VV) has not been determined by its consumption level. The aim of this study was to investigate the association between alcohol intake and VV in an elderly general population. Using a cross-sectional approach, the Shimane CoHRE Study data, comprising a total of 1060 participants, were analyzed. By multivariate regression analysis adjusted with basic characteristics, past work history, lifestyle-related factors and medical history, compared with non-drinkers, mild drinkers (<20.0 g/day) showed a significantly lower adjusted odds ratio (aOR) of VV (aOR = 0.64, P = 0.036). In a similar way, regular drinkers (1-5 days/week) showed a significantly lower aOR of VV when compared with occasional drinkers (aOR = 0.57, P = 0.032). VV and alcohol intake showed J-curve relationships. In a stratified analysis by alcohol consumption levels, the association of smoking and VV were also observed in moderate to heavy drinkers and habitual drinkers. These findings can provide better understanding of pathophysiological mechanism and be used for evidence-based patient education.
DOI 10.1111/1346-8138.15022
PMID 31353631