ミシマ ユウイチロウ   Mishima Yuichiro
  三嶋 雄一郎
   所属   京都産業大学  生命科学部 先端生命科学科
   職種   教授
言語種別 英語
発行・発表の年月 2004/02
形態種別 研究論文
査読 査読あり
標題 A novel gene, the protein product of which is mainly expressed in germline cells and in the dorsal structures of Xenopus
執筆形態 その他
掲載誌名 DEVELOPMENT GENES AND EVOLUTION
出版社・発行元 SPRINGER-VERLAG
巻・号・頁 214(2),pp.89-95
著者・共著者 S Yamakita,Y Mishima,K Ikenishi
概要 A novel cDNA was isolated from a Xenopus cDNA library using an antibody recognizing the germ plasm-specific germinal granules. The protein product of the gene (Xdsg) was detected on the germinal granules of the cleaving embryo as determined by immunoelectron microscopy. The spatio-temporal distribution of the RNA transcript and protein product of the gene was investigated in oocytes and embryos. The protein was detected in the germ plasm and the germline cells from the cleavage to the tadpole stages, while both the protein and RNA transcript were prominent in the dorsal structures from the tailbud stage onward. The present study has shown for the first time that the protein product of the Xdsg gene was present on the germinal granules in Xenopus.
DOI 10.1007/s00427-004-0382-8
ISSN 0949-944X
PMID 14747946