イタノ ナオキ
ITANO NAOKI
板野 直樹 所属 京都産業大学 生命科学部 先端生命科学科 職種 教授 |
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言語種別 | 英語 |
発行・発表の年月 | 1996/05 |
形態種別 | 研究論文 |
査読 | 査読あり |
標題 | Molecular cloning of human hyaluronan synthase |
執筆形態 | その他 |
掲載誌名 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
出版社・発行元 | ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS |
巻・号・頁 | 222(3),pp.816-820 |
著者・共著者 | N Itano,K Kimata |
概要 | We report here the cDNA sequence of human hyaluronan synthase. The cDNA clone was isolated from a human fetal brain cDNA library by screening with a DNA probe generated from the coding sequence of murine hyaluronan synthase. It contains a 2107 bp cDNA insert which is composed of a 1629 bp open reading frame and a short segment of the 3'-untranslated region. Comparative analysis of the predicted coding region with the murine hyaluronan synthase sequence indicates 84.4% and 96.0% identity in nucleotide sequence and amino acid sequences, respectively. Northern analysis indicated that the gene was ubiquitously expressed in various human tissues. (C) 1996 Academic Press, Inc. |
ISSN | 0006-291X |