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エンドウ トシヤ
ENDO TOSHIYA
遠藤 斗志也 所属 京都産業大学 生命科学部 先端生命科学科 職種 客員教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2009/08 |
| 形態種別 | 研究論文 |
| 査読 | 査読あり |
| 標題 | Multiple pathways for mitochondrial protein traffic |
| 執筆形態 | その他 |
| 掲載誌名 | BIOLOGICAL CHEMISTRY |
| 出版社・発行元 | WALTER DE GRUYTER & CO |
| 巻・号・頁 | 390(8),pp.723-730 |
| 著者・共著者 | Toshiya Endo,Koji Yamano |
| 概要 | Mitochondria are two-membrane bounded organelles consisting of 1000-2000 different proteins, most of which are synthesized in the cytosol and subsequently imported into mitochondria. The imported proteins are further sorted to one of the four compartments, the outer membrane, intermembrane space, inner membrane, and matrix, mostly following one of the five major pathways. Mitochondrial protein import and sorting are mediated by the translocator complexes in the membranes and chaperones in the aqueous compartments operating along the import pathways. Here, we summarize the expanding knowledge on the roles of translocators, chaperones, and related components in the multiple pathways for mitochondrial protein trafficking. |
| DOI | 10.1515/BC.2009.087 |
| ISSN | 1431-6730 |