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若林 憲一 所属 京都産業大学 生命科学部 産業生命科学科 職種 教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2009 |
| 形態種別 | その他 |
| 査読 | 査読あり |
| 標題 | Analysis of Redox-Sensitive Dynein Components |
| 執筆形態 | その他 |
| 掲載誌名 | CILIA: MOTORS AND REGULATION |
| 出版社・発行元 | ELSEVIER ACADEMIC PRESS INC |
| 巻・号・頁 | 92,pp.153-161 |
| 著者・共著者 | Ken-ichi Wakabayashi |
| 概要 | Redox-based regulation plays important roles in many cellular activities. Thioredoxins, one of the best characterized class of proteins involved in cellular redox regulation, are conserved components of eukaryotic ciliary/flagellar axonemal dyneins. Studies with Chlamydomonas showed that, under varying redox conditions, dynein-associated thioredoxins interact with different proteins through disulfide bonds and, as a consequence, flagella change their manner of beating. This chapter provides an overview of techniques for estimating and modulating the redox state of axonemal proteins, as well as for searching for redox-regulated proteins in the axoneme. |
| DOI | 10.1016/S0091-679X(08)92010-0 |
| ISSN | 0091-679X |
| PMID | 20409804 |