|
カトウ ケイコ
KATO KEIKO
加藤 啓子 所属 京都産業大学 生命科学部 先端生命科学科 職種 教授 |
|
| 言語種別 | 英語 |
| 発行・発表の年月 | 1998/03 |
| 形態種別 | その他 |
| 標題 | Expression of neuropsin mRNA in the mouse embryo and the pregnant uterus |
| 執筆形態 | その他 |
| 掲載誌名 | JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY |
| 出版社・発行元 | HISTOCHEMICAL SOC INC |
| 巻・号・頁 | 46(3),pp.313-320 |
| 著者・共著者 | ZL Chen,Y Momota,K Kato,M Taniguchi,N Inoue,S Shiosaka,S Yoshida |
| 概要 | Neuropsin is a novel serine protease whose mRNA is expressed in the mouse central nervous system. We examined the expression of neuropsin mRNA during embryonic development using Northern and in situ hybridization in non-neural tissues. The pregnant uterus showed strong expression of neuropsin mRNA, whereas the nonpregnant uterus did not express this mRNA. Expression was first detected in the primary decidual zone at 5.5 days post coitum and was maximized at 10 days post coitum, decreasing remarkably thereafter. During mouse organogenesis, neuropsin expression was observed in the developing heart, lung, thymus, pituitary, choroid plexus, and epithelial linings of the skin, oral cavity, tongue, esophagus, and forestomach. In adult mouse organs, neuropsin mRNA was expressed in epithelial tissues covered by keratinocytes with moderate density, whereas low expression was observed in lung, thymus, and spleen. Neuropsin mRNA expression in developing organs and adult keratinocytes suggests that neuropsin is associated with extracellular matrix modifications and cell migrations. |
| ISSN | 0022-1554 |