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ハマノ ツヨシ
HAMANO TSUYOSHI
濱野 強 所属 京都産業大学 現代社会学部 健康スポーツ社会学科 職種 教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2015/03 |
| 形態種別 | 研究論文 |
| 査読 | 査読あり |
| 標題 | Depression, stroke and gender: evidence of a stronger association in men |
| 執筆形態 | その他 |
| 掲載誌名 | JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY |
| 出版社・発行元 | BMJ PUBLISHING GROUP |
| 巻・号・頁 | 86(3),pp.319-323 |
| 著者・共著者 | Tsuyoshi Hamano,Xinjun Li,Sara Larsson Lonn,Toru Nabika,Kuninori Shiwaku,Jan Sundquist,Kristina Sundquist |
| 概要 | Background/aims Depression is associated with an increased risk for stroke. The aim of this study was to examine whether demographic and socioeconomic factors modify this association.
Methods This follow-up study comprised 137 305 men and 188 924 women aged >= 30 years from a nationwide sample of primary healthcare centres in Sweden. We identified 4718 first-ever stroke cases (2217 men and 2501 women) during the follow-up period (2005-2007). Multilevel logistic regression models were used to calculate ORs and examine interactions in order to determine whether the association between depression and stroke differs by demographic or socioeconomic factors. Results Depression was associated with significantly greater odds of stroke after adjustment for potential confounding factors (OR=1.22, 95% CI 1.08 to 1.38). Interaction tests showed that the effect of depression on stroke was higher in men compared with women (the difference in OR between men and women was 1.30, 95% CI 1.01 to 1.68), that is, the association between depression and stroke was modified by gender. Conclusions Our findings suggest that the depression-stroke association is modified by gender. Further studies are required to examine the underlying mechanisms in men and women. |
| DOI | 10.1136/jnnp-2014-307616 |
| ISSN | 0022-3050/1468-330X |