ハマノ ツヨシ   HAMANO TSUYOSHI
  濱野 強
   所属   京都産業大学  現代社会学部 健康スポーツ社会学科
   職種   教授
言語種別 英語
発行・発表の年月 2022
形態種別 研究論文
査読 査読あり
標題 Changes in the urinary sodium-to-potassium ratio are associated with blood pressure change in older Japanese adults: a 7-year longitudinal study
執筆形態 その他
掲載誌名 Journal of Clinical Medicine
掲載区分国外
巻・号・頁 11(17),pp.5093
著者・共著者 Abe T, Endo T, Hamano T, Okuyama K, Yano S
概要 Studies on the association between sodium-to-potassium (Na/K) ratio changes and blood pressure (BP) changes among older adults are limited. This 7-year longitudinal study examined the association between Na/K ratio changes (evaluated using spot urine tests) and BP changes among older Japanese adults. Data were collected from 432 participants (mean age: 70.3±4.4; range: 65-84 years) in 2012 and 2019. Changes in BP and the Na/K ratio over 7 years were calculated by subtracting baseline values from values noted during a follow-up survey. The median systolic and diastolic BP (SBP) and (DBP) changes after 7 years were 4 (IQR, -7, 14) and -1 (IQR, -9, 5) mmHg, respectively. The median Na/K ratio was changed during the follow-up period by -0.2 (IQR, -1.3, 0.7). A generalized linear model indicated that Na/K ratio changes were positively associated with SBP (B = 2.03, p < 0.001) and DBP (B = 0.62, p = 0.021) changes. In the non-antihypertensive medication-using group, urinary Na/K ratio changes were associated with SBP and DBP changes (B = 2.39, p = 0.001; B = 0.99, p = 0.033). In the antihypertensive medication user group, urinary Na/K ratio changes were associated with SBP changes (B = 1.62, p = 0.015). We confirmed the association between changes in the Na/K ratio and changes in BP.
DOI 10.3390/jcm11175093
PMID 36079021