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エンドウ トシヤ
ENDO TOSHIYA
遠藤 斗志也 所属 京都産業大学 生命科学部 先端生命科学科 職種 客員教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 1991/11 |
| 形態種別 | 研究論文 |
| 査読 | 査読あり |
| 標題 | COOPERATIVE BINDING OF HSP60 MAY PROMOTE TRANSFER HSP70 AND CORRECT FOLDING OF IMPORTED PROTEINS IN MITOCHONDRIA |
| 執筆形態 | その他 |
| 掲載誌名 | FEBS LETTERS |
| 出版社・発行元 | ELSEVIER SCIENCE BV |
| 巻・号・頁 | 293(1-2),pp.1-3 |
| 著者・共著者 | T ENDO |
| 概要 | I propose that a molecular chaperone hsp60 binds to and dissociates from the unfolded polypeptide or folding intermediate in a positively co-operative manner, but another chaperone hsp70 shows no such co-operativity. This could simply explain the fact that the protein newly imported in the mitochondrial matrix is transferred from hsp70 to hsp60 and hsp60 promotes correct folding of the substrate protein while hsp70 does not. |
| ISSN | 0014-5793 |