エンドウ トシヤ   ENDO TOSHIYA
  遠藤 斗志也
   所属   京都産業大学  生命科学部 先端生命科学科
   職種   客員教授
言語種別 英語
発行・発表の年月 1995/01
形態種別 研究論文
査読 査読あり
標題 IDENTIFICATION OF YEAST MAS17 ENCODING THE FUNCTIONAL COUNTERPART OF THE MITOCHONDRIAL RECEPTOR COMPLEX PROTEIN MOM22 OF NEUROSPORA-CRASSA
執筆形態 その他
掲載誌名 FEBS LETTERS
出版社・発行元 ELSEVIER SCIENCE BV
巻・号・頁 357(2),pp.202-206
著者・共著者 M NAKAI,T ENDO
概要 MOM22 of Neurospora crassa,vas suggested to be required for the transfer of mitochondrial precursor proteins from the receptors to the protein translocation machinery. We isolated a yeast mutant the viability of which depended on the expression of the introduced N. crassa MOM22 gene. The mutant cells showed defects in protein import into mitochondria when the cells were depleted of MOM22. By screening for suppressor genes for the mutant, we could identify the yeast gene MAS17 encoding the functional counterpart of MOM22. The MAS17 gene was found to be essential for the viability of yeast cells.
ISSN 0014-5793