ミシマ ユウイチロウ
Mishima Yuichiro
三嶋 雄一郎 所属 京都産業大学 生命科学部 先端生命科学科 職種 教授 |
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言語種別 | 英語 |
発行・発表の年月 | 2014/05 |
形態種別 | その他 |
査読 | 査読あり |
標題 | Elements and machinery of non-coding RNAs: toward their taxonomy |
執筆形態 | その他 |
掲載誌名 | EMBO REPORTS |
出版社・発行元 | WILEY |
巻・号・頁 | 15(5),pp.489-507 |
著者・共著者 | Tetsuro Hirose,Yuichiro Mishima,Yukihide Tomari |
概要 | Although recent transcriptome analyses have uncovered numerous non-coding RNAs (ncRNAs), their functions remain largely unknown. ncRNAs assemble with proteins and operate as ribonucleoprotein (RNP) machineries, formation of which is thought to be determined by specific fundamental elements embedded in the primary RNA transcripts. Knowledge about the relationships between RNA elements, RNP machinery, and molecular and physiological functions is critical for understanding the diverse roles of ncRNAs and may eventually allow their systematic classification or "taxonomy." In this review, we catalog and discuss representative small and long non-coding RNA classes, focusing on their currently known (and unknown) RNA elements and RNP machineries. |
DOI | 10.1002/embr.201338390 |
ISSN | 1469-221X/1469-3178 |
PMID | 24731943 |