教員情報 - 林　到炫 | 京都産業大学

林　到炫

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京都産業大学生命科学部先端生命科学科

職種准教授

著書・論文歴
2026/01/08	論文	Structural basis for the subtype-selectivity of KCa2.2 channel activators Nature Communications
2025/11/25	論文	Structural insights into the G-protein subtype selectivity revealed by human sphingosine-1-phosphate receptor 3–G q complexes Proceedings of the National Academy of Sciences
2025/08/07	論文	Discovery and development of an oral analgesic targeting the α2B adrenoceptor Proceedings of the National Academy of Sciences 122 (32)
2025/04/17	論文	Cryo-EM structures of the small-conductance Ca2+-activated KCa2.2 channel Nature Communications
2025/01/20	論文	The structure and function of the ghrelin receptor coding for drug actions. Nature structural & molecular biology
2024/09/16	論文	Neurotransmitter recognition by human vesicular monoamine transporter 2. Nature communications 15 (1),7661-7661頁
2024/02/05	論文	Crystal structure reveals the binding mode and selectivity of a photoswitchable ligand for the adenosine A2A receptor. Biochemical and biophysical research communications 695,149393-149393頁
2024	論文	グレリン受容体のリガンド認識機構および活性化機構の構造学的洞察日本薬学会年会要旨集(Web) 144th
2023/11	論文	肥満における5G(GLP-1、GIP、Glucagon、Ghrelin、Gut hormone) 基礎研究と臨床研究グレリン受容体の構造的洞察(The 5Gs in Obesity(GLP-1, GIP, Glucagon, Ghrelin and Gut hormone): Basic and Clinical Research Structural Insights into Ghrelin Receptor) 肥満研究 29 (合同学術集会抄録集),157-157頁
2023/10/20	論文	Structural insights into the agonists binding and receptor selectivity of human histamine H4 receptor. Nature communications 14 (1),6538-6538頁
2023/09/18	論文	Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography Nature Chemistry
2022/12/01	論文	Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor. Structure (London, England : 1993) 30 (12),1582-1589頁
2021/08/19	論文	S1PR3-G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation. Cell chemical biology 28 (8),1132-1144頁
2020/12/22	論文	Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone. Nature communications 11 (1),6442-6442頁
2020/04/07	論文	The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone. Structure (London, England : 1993) 28 (4),418-425頁
2020/03/01	論文	Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals. IUCrJ 7 (Pt 2),306-323頁
2019/09	論文	生理活性物質アンジオテンシンIIの結合によるアンジオテンシンII受容体活性化機構の構造基盤日本生化学会大会プログラム・講演要旨集 92回,[1T03m-04]頁
2019/02	論文	Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine. Nature structural & molecular biology 26 (2),121-128頁
2018/03	論文	Ligand complex structures of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 and its conformational change. FEBS open bio 8 (3),314-324頁
2018/01/02	論文	Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA. Structure (London, England : 1993) 26 (1),7-19頁
2016/12/23	論文	A three-dimensional movie of structural changes in bacteriorhodopsin. Science (New York, N.Y.) 354 (6319),1552-1557頁
2015	論文	機能性抗体を用いたアゴニスト結合型アデノシンA2a受容体の結晶構造解析 GPCR研究会プログラム・抄録集 12th
2014	論文	Mutational and crystallographic analysis of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813: Interconversion between oxidase and monooxygenase activities. FEBS open bio 4,220-8頁
2012	論文	Crystal structures of glycoside hydrolase family 51 α-L-arabinofuranosidase from Thermotoga maritima. Bioscience, biotechnology, and biochemistry 76 (2),423-8頁